台灣地區市售安莫西林(AMOXICILLIN)膠囊製劑力價之調查

AN INVESTIGATION FOR THE POTENCY OF AMOXICILLIN CAPSULES IN TAIWAN AREA

本計畫於民國80年度，由全省各縣市抽購國產及進口安莫西林（Amoxicillin）口服膠囊製劑共50件，其中國產47件，進口3件。依據U.S.P. XXII之高效液相層析法（High Performance Liquid chromatograph）、日本抗生物質醫藥品基準解說（MRAP）上所載之分光光度法及微生物法測定其力價，結果有4件未達合格標準，不合格率為8.0%。

In order to understand the potency of amoxicillin capsules, fifty samples (47 domestic, 3 imported) were purchased from different counties and cities in Taiwan during September 1990 to March 1991. All of the samples were determin performance liquid chromatographic method, the cylinder- plate method and optical method as described in the United State Pharmacopeia and the Minimum Requirements for Antibiotic Products of Japan. The results showed that 4 samples (8.0%) failed to meet the potency requirement of the government regulation (90-120 %).