| 英文摘要 |
There is an increasing interest in the use of various biomarkers to assess the overall oxidative stress because of its implication in aging, cancer and several degenerative diseases. Urine is easy to collect and permits a non-invasive approach for measuring biological substances. In the past decades, urinary biomarkers of oxidative stress have been widely used both in research and clinical investigations and this also underscores the importance of having accurate and reliable assays. This article reviews the use of urinary biomarkers of oxidative stress (including oxidatively damaged DNA, oxidatively damaged RNA and the products of lipid peroxidation), and the pros and cons of the currently available assays for their measurement. |
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