眼科民間保健藥用植物毛山葡萄之成分研究

Study on the Constituents of Ampelopsis brevipedunculata var. ciliate(Nakai) Lu.of the Ophthalmic Folk Medicines

由台灣產民間治療眼疾保健植物毛山葡萄Ampelopsis brevipedunculata var. ciliate（Nakai） Lu.分離出四種三萜類化合物（lupeol, lupenone, squalene, cycloartenol）兩種酚類化合物，並用EI-MS，IR，1H-NMR，13C-NMR等光譜分析技術測定成分的化學結構。其中化合物lupeol及squalene，據文獻報導，它能促進視網膜色素上皮細胞（RPE）的吞噬作用。

Fourknowntriterpenoids(lupeol, lupenone, squalene, cycloartenol)and two phenolic compounds were isolated fromAmpelopsis brevipedunculatavar. ciliate(Nakai) Lu.of theOphthalmic Folk Medicines in Taiwan.According to the literature, lupeol and squalene can enhance Retinal Pigment Epithelial (RPE) cell phagocytosisin retina. Structure determination was carriedout by spectral techniquessuch as,EI-MS, IR, 1H-NMRand 13C-NMR.