以皮膚炎表現的蘭格罕細胞組織球增生症：一例報告

A Case of Langerhans Cell Histiocytosis Presented as Prolonged Eczematous Rash

蘭格罕細胞組織球增生症是一種組織球異常增生的疾病，會侵犯單一或多種身體器官，大部分發生於兒童。單一皮膚或骨頭侵犯其預後良好，而多種器官的侵犯有惡性疾病的特質，須給予化學治療，在小於一歲兒童皮膚為最常見表徵，型態上不易和常見皮膚炎作區別，容易延誤診斷及治療。此病例為一九個月兒童，經半年皮膚炎治療無效，最後證實為蘭格罕細胞組織球增生症，並接受化學治療。目的為提醒臨床醫師，若病人有難以控制的皮膚疾病，須將此病列入鑑別，施以皮膚切片確定診斷，若確診，並給予至少五年的追蹤。

We presented a 9-month-old boy had multiple, pinkish-yellow, erythematous vesicles on his trunk 6 months ago. There were also many erythematous, moist and erosive eruptions on scalp, both axillae, inguinal regions and intergluteal sulcus. He was treated as having varicella and seborrheic dermatitis. However the symptoms did not improve. Histopathological investigation of the lesions revealed eosinophil with positive immunostaining. He was diagnosed with Langerhans cell histiocytosis and received chemotherapy.