英文摘要 |
Purpose: Dyslipidemia and elevated low-density lipoprotein cholesterol (LDL-C) have been identified as risk factors for atherosclerosis and cardiovascular disease. The aim of this study was to evaluate the prevalence of and factors related to elevated LDL-C among young workers in southern Taiwan. Materials & Methods: We conducted a cross-sectional study by analyzing the database from the 2007 annual health examination of a company in southern Taiwan. Anthropometric measurements, sex, age, serum lipid profile, blood pressure, glutamic-pyruvic transaminase (GPT), and fasting glucose were recorded. Patients were divided into 4 categories according to their level of LDL-C: <130 mg/dL, 130-159 mg/dL, 160-189 mg/dL, >190 mg/dL; and elevated LDL-C was defined >130 mg/dL. Result: A total of 16,123 workers, 7,556 (46.9%) men and 8,567 (53.1%) women, were recruited. The mean serum level of LDL-C in the men (115.6±29.4 mg/dL) was higher than that in the women (104.1±27.0 mg/dL) ( p<0.001). The overall prevalence of elevated LDL-C was 21.3%. The older men with higher BMI and blood pressure, and abnormal fasting glucose, GPT, triacylglycerol (TG), and high-density lipoprotein cholesterol (HDL-C) had a higher prevalence of elevated LDL-C. After adjusting for age, sex, BMI, blood pressure, fasting glucose, GPT, TG, and HDL-C, male sex, older age, higher BMI, higher blood pressure, impaired fasting glucose, and abnormal GPT, TG, and HDL-C were independent risk factors of elevated LDL-C. Conclusion: Elevated LDL-C was prevalent, and its risk factors were similar to those for cardiovascular disease in this young working population. |