電鍍業勞工鉻暴露與氧化傷害評估研究

A Study of Chromium Exposure and Oxidative Stress of Electroplating Workers

本研究針對台灣地區六家硬鉻電鍍工廠32位直接電鍍槽作業勞工與68位對照組勞工，進行評估暴露對人體氧化傷害之影響，直接電鍍槽作業勞工、與對照組勞工平均尿中鉻濃度分別為13.5μg/ gcreatinine、與4.1μg/ g creatinine，經常用對數轉換後，直接電鍍槽作業勞工尿液中鉻平均濃度顯著高於與對照組（p<0.001）。直接電鍍槽作業勞工、與對照組勞工平均尿中丙二醛濃度分別為3.5μmol/ g creatinine、與2.4μmol/ g creatinine，經常用對數轉換後，直接電鍍槽作業勞工尿液中丙二醛平均濃度顯著高於與對照組（p=0.032），但32 位直接電鍍槽作業勞工之尿中鉻濃度與尿中丙二醛濃度無顯著相關性存在。

This study was to evaluate whether exposure to chromium induced oxidative stress in human. The study involved 32 workers directly working with electroplating tanks and a reference group of 68 control subjects among six electroplating factories. The mean urine chromium concentrations of workers directly working with electroplating tanks and reference group were 13.5 and 4.1μg/ g creatinine, respectively. The mean chromium concentration in urine of the workers directly working with electroplating tanks was significantly higher than the control group (p<0.001) after normalization of the curve on log-normal coordinates. The mean urine malondialdehyde (MDA) concentrations of workers directly working with electroplating tanks and reference group were 3.5 and 2.4μmol/ g creatinine, respectively. The mean MDA concentration in urine of workers directly working with electroplating tanks was significantly higher than the control group (p=0.032) after normalization of the curve on log-normal coordinates. There was no significant correlation between urine chromium concentrations and MDA concentrations for the 32 workers directly working with electroplating tanks.