隨著醫療科技進步，生命延長的同時也引發對自主善終的重視。《病人自主權利法》於2019年施行，保障病人在特定臨床情境下表達醫療意願， 專科護理師（Nurse Practitioner, NP）在推動預立醫療照護諮商（Advance Care Planning, ACP）中扮演重要角色。專科護理師憑藉臨床實務、溝通協調、宣導與治療管理等能力，不僅協助病人及家屬釐清醫療選擇，更能促進團隊合作，確保病人意願落實於臨床實踐。本文透過文獻探討及臨床案例，論述專師如何引導末期病人完成預立醫療決定及醫療委任代理人簽署，強調專師於病人自主權利推動歷程中，提升醫病溝通品質、減少無效醫療及促進善終照護之關鍵貢獻。藉由強化專科護理師的角色功能，能進一步促使病人在生命末期獲得尊嚴、舒適且符合個人價值觀的照護。

Advancements in medical technology have prolonged life but also heightened awareness of the need for autonomous end-of-life care decision-making. Enacted in 2019, the Patient Right to Autonomy Act protects patients’ rights to express their medical preferences under specific clinical conditions. Nurse practitioners (NPs) play a pivotal role in implementing Advance Care Planning (ACP), drawing on their expertise in clinical practice, communication and coordination, advocacy, and treatment manage-ment. NPs assist patients and their families in navigating complex medical decisions, promote inter-disciplinary collaboration, and ensure the integration of patients’ preferences into clinical care. This article employs a literature review and clinical case analysis, to examine how NPs guide terminally ill patients through the completion of advance medical directives and the designation of healthcare prox-ies. The findings underscore the critical contributions of NPs in enhancing healthcare communication, minimizing non-beneficial medical interventions, and advancing high-quality end-of-life care. By strengthening the functional role of nurse practitioners, patients are more likely to receive end-of-life care that is dignified, comfortable, and aligned with their personal values.