In the face of the increasing demands for long-term care as a result of aging population, longterm care facilities are confronted by the risks of healthcare- associated infections and infectious disease clusters because of the people they serve and their facilities’ environmental factors. Hence, implementing infection prevention planning is crucial for ensuring resident and healthcare staffrelated safety and care quality. This article mainly describes the establishment of infection control planning and indicators selection, indicators audit and infections surveillance, and implemented infection surveillance -associated critical mechanisms and steps including surveillance planning, surveillance data collection and analysis, infection rates interpretation, information communication, and evaluating surveillance systems, and expect to provide reference and application.