英文摘要 |
It has been shown that the concentration of vitamin C may be significant decreased in cancer patients compared to healthy subjects. Although the results of preclinical studies showed promising efficacy of the intravenous administration, the result of clinical trials are inconclusive and have not delivered solid evidence of clinical efficacy in the treatment of cancer. At the pharmacological dose (1 mM) vitamin C decreased cell proliferation, and inflammation, and induced apoptosis. Therefore, high doses of vitamin C are administered intravenously by complementary and alternative medicine as an additional treatment for patients with respect to its low price, limited number of side effects, improvement of the quality of life of cancer patients and somewhat anti-cancer activity, it seems there is a solid rationale for the possible introduction of vitamin C administration via intravenous infusion to the treatment of selected malignant neoplasms. |