繞射物質化：論免疫記憶的多重時間性

Diffractive Mattering: On the Multiple Temporalities of Immunological Memory

在這篇文章，我將把感染和免疫視為化為分子的微型政治事件，從中梳理跨物種共同演化中，免疫力的展露、疊加與干擾，以及病原體的逃避機制等議題，特別是其中所涉及的微尺度介面動態，如何充滿物質－－記號的交換、協商、解組與重構。首先，從身體如何可能的觀點出發，探討免疫學中的自我模型和非自我模式的形構。其次，闡述在技術分子轉向的時代，分子感受力在微觀層次上的跨界性質，及其文化政治意涵。第三、提出行星生命演化做為一種繞射物質化的觀點，強調政治生活做為一種異質共構的可能性。第四，繪製幾種免疫化策略中呈現出的繞射模式，包括細菌對抗噬菌體的後天免疫系統CRISPR、巨型病毒對抗噬病毒體的免疫系統MIMIVIRE，以及巨型病毒、噬病毒體和原生生物宿主之間的多重向度網絡，乃至於Covid-19混種免疫力的相關研究等。最後，在結論中，我思考繞射的免疫多重時間性如何穿越自我和他者的邊界，在防守中不斷協商，動態地共構出我們行星生物圈中所體現的跨物種記憶。

In this article, I will treat infection and immunity as micro-political events of becoming molecular and explore the emergence, superposition, and interference of immunity, and the escape mechanisms of pathogens in transspecies coevolution, especially the microscale interface dynamics full of material-semiotic exchange, negotiation, deconstruction, and reconstruction. First, I discuss the formation of the self and nonself patterns in immunology to examine how the body is possible. Secondly, I articulate the cross-boundary nature of molecular sensibility and its cultural and political significance at the microscopic level in the era of techno-science molecular turn. Third, I put forward the viewpoint of planetary life evolution as a mode of diffractive mattering, emphasizing the possibility of political life as a heterogeneous coconfiguration. Fourth, I map the diffraction patterns exhibited in several immunization strategies, including the acquired immune CRISPR system against phages in bacteria, the MIMIVIRE system against virophages in giant viruses, and the multi-dimensional network among giant viruses, virophages, and protist hosts, as well as the research on Covid-19 hybrid immunity. Finally, I consider how diffractive immune temporalities traverse the borders between self and other, constantly negotiate in defense, and co-constitute the dynamic trans-species memory embodied in our planetary biosphere.