子宮頸淋巴瘤的檢視

Primary cervical lymphoma

原發性子宮頸淋巴瘤乃婦科癌病中罕見的一種惡性腫瘤。淋巴瘤主要發生在有淋巴球的器官，如脾臟、胸腺、淋巴結，和轉移的其它部位。原發性子宮頸淋巴瘤的診斷是困難的，臨床上其產生的症狀主要有陰道出血或有分泌物、尿道症狀或骨盆腔疼痛等。原發性子宮頸淋巴瘤需與下列疾病區分，包括子宮頸肌瘤、分化不良鱗狀上皮癌、慢性發炎和惡性肉瘤。治療建議用6個療程的R-CHOP（rituximab、cyclophosphamide、doxorubicin、vincritine和prednisone）的化學治療，加上放射線治療，會有不錯的效果。如能早期診斷出子宮頸淋巴瘤，能立即進行化學治療和放射線治療，可避免不需要的手術。

Primary cervical lymphoma is arare malignancy encountered by gynecologic oncologist. Typically, lymphoma arises in lymphatic organs such as the spleen, thymus, or lymph nodes and spreads to other sites. Primary cervical lymphoma is difficult to preoperatively. Clinically, it often presents with vaginal bleeding or discharge, urinary symptoms or pelvic pain. Differential diagnosis of primary cervical lymphoma should include cervical fibroid, poorly differentiated squamous cell carcinoma, chronic inflammation, and sarcoma. The recommended treatment might be six courses of R-CHOP (rituximab, cyclophosphamide, doxorubicin, vineristine and prednisone) in addition of radiotherapy, is associated with favorable clinical outcomes. The prospective diagnosis of lymphoma avoids unnecessary surgery and enables the immediate institution of chemotherapy or radiation therapy.