The purpose of this project was to improve the rate of accuracy of aerosol therapy in pediatric ward. Inadequate implementation of aerosol therapy in a pediatric ward was found during ward rounds. Possible causes were: (1) caregivers were unclear about the purpose and methods of the therapy; (2) the hospitalized children were afraid of the noise and fumes made during therapy; (3) frequently changes of caregivers without handover between family members; (4) inadequate understanding on aerosol therapy by the nurses. From April 3 to October 31, 2017, we established improvement measures, including continuing education, revision of the SOP of aerosol therapy, preparation of education flyers and films, and design of therapy games. Results showed that the rate of accuracy of aerosol therapy increased from 12.3% to 93.1%. The cooperation rate of the hospitalized children increased from 25.4% to 98.3%. The rate of handover by the caregivers rose from 13.4% to 86.7%. The nurses’ knowledge of aerosol therapy rose from 52.4 points to 100 points. This project serve as a reference for other forms of pediatric care.