甲狀舌骨囊腫惡性腫瘤：個案報告及治療討論

Thyroglossal Duct Cyst Carcinoma : Case Report and Treatment Discussion

甲狀舌骨囊腫是最常見的甲狀腺先天性異常，發生率在成人約佔7%左右。其大多為前頸部無症狀之良性腫塊，而惡性變化則相當少見，一般來說發生率低於1%。組織類型上超過九成皆為乳突細胞型，約有4%為鱗狀細胞癌。對於此惡性腫瘤的治療上，除了完整的手術切除外，是否需合併甲狀腺組織的切除，及術後輔助性放射碘治療，至今仍存在許多爭議。在此，我們報告一個52歲女性之甲狀舌骨囊腫的甲狀腺乳突癌病患，並對其臨床診斷及治療方式提出討論。

 

Thyroglossal duct cyst (TGDC) is the most common congenital thyroid developmental anomaly and also the most common congenital neck anomaly. Incidence of TGDC in the adult population is estimated at 7 %. However, malignant changes are rare and occur in less than 1% of TGDC. Over 90% comprises papillary types while squamous cell carcinoma comprises 4.3%. Here we report the case of a 52-year-old female with unexpected finding of papillary carcinoma arising from TGDC. Subsequent total thyroidectomy and radioactive iodine treatment is performed.