利用前節光學同調斷層掃描分析帶狀皰疹病毒眼症:病例報告

AS-OCT Manifestations in a Case of Zoster Disciform Keratitis with Immune Ring

在本病例報告中，一名右眼患有帶狀皰疹病毒眼症的80歲女性病患接受了前節光學同調斷層掃描檢查。掃描的切面影像中顯示，混濁及發炎現象主要發生在角膜基質的前半部。在光學同調斷層掃描的厚度圖譜中，可看見在免疫環 (immune ring)區域，角膜基質有明顯環狀變薄情形，角膜上皮也環狀增生變厚以補償因發炎變薄的角膜基質，這樣的變化可使得角膜表面更為平滑。藉由前節光學同調斷層掃描技術的輔助，帶狀皰疹病毒眼症所造成的組織結構的變化現在可被分層具象化研究並幫助其診斷。

 

Anterior Segment-Optical coherence tomography (AS-OCT) was performed on an 80-year-old woman with a history of Herpes Zoster Ophthalmicus on her right eye. Cross-section image showed opacity and stromal keratitis mainly in the anterior half of stroma. From the AS-OCT pachymetry map, an overall thinning of cornea was observed on the region within immune ring. By examining both pachymetry map and epithelium map, thickening of the epithelium and thinning of stroma at the ring site were found, resulting in a smoother cornea. With the aid of AS-OCT, the ultra-structure of the cornea in patients of Herpes Zoster Ophthalmicus could now be visualized layer by layer and in turn assist diagnosis.