Background and purpose: Schmorl’s nodes (SNs) represent a thoracolumbar lesion, which are defined histologically as a loss of the nuclear material of intervertebral discs through the cartilage plate, growth plate, and endplate into the vertebral body. We report two cases of symptomatic SNs and assess the effect of two different surgical procedures to treat severe lower back pain caused by traumatic SNs. Case presentation: Two cases of symptomatic SNs with a history of trauma are presented. One involved a 15-year-old male patient and the other involved a 66-year-old female patient. The results of magnetic resonance imaging and X-ray confirmed the diagnosis of SNs. The male patient underwent laminotomy, discectomy, and insertion of a Rocker interspinous spacer under general anesthesia. The female patient underwent percutaneous vertebroplasty under local anesthesia. The visual analog scale was used to measure lower back pain before and after surgery. Both patients were asymptomatic at a 3-month follow-up; however, the male patient was readmitted due to new SN lesions 6 months after surgery. Conclusion: Both procedures were effective in relieving lower back pain from SNs, had a relatively short recovery time, and resulted in no postoperative complications. However, the male patient required further follow-up due to new lesions.