Complications of hyperphosphatemia not only increase medical costs but also threaten the life and health of patients; it is therefore crucial to reduce elevated serum phosphate levels in patients and keep it below ≦5.5 mg/dl. Results of routine patient blood tests between October 2013 and March 2014 showed that the percentage of patients with serum phosphate levels above 5.5 mg/dl was as high as 27%~36% every month. The goal of the project team was to reduce the incidence of hyperphosphatemia. Issue identification: The nursing manual is cumbersome to carry with fonts that are too small to read; the types of foods with high phosphate levels varied greatly, and oral health education was difficult to memorize; food prepared by family members and forgetting to bring medications when eating out. Improvement strategies: The nursing manual was revised and multimedia health education videos produced; portable tools were designed for patients such as bottles for the phosphate binder that can be carried anywhere, key chains listing foods high in phosphorus, as well as diagrams to help with memorization. Upon implementation, the incidence of patient serum phosphate levels above 5.5 mg/dl dropped from 29.1% to 17.9%. The strategy not only helped to control patients’serum phosphate levels but also improved quality of care as well.