針灸穴位介入措施改善氣喘病人之肺功能、免疫功能及生活品質：隨機控制試驗之系統性文獻回顧

Acupuncture Point Interventions Improve Lung Function, Immune System, and Quality of Life in Asthma Patients: A Systematic Review of Randomized Controlled Trials ABSTRACT

背景：氣喘照護著重於規律地控制症狀與肺功能受損。雖然有系統性文獻回顧的結論支持中醫對氣喘的治療成效，但是所使用的穴位仍需進一步釐清。目的：本研究旨在以統性文獻回顧法歸納針灸穴位使用於氣喘緩和期對肺功能、免疫功能及生活品質之改善。方法：本研究在七個電子資料庫進行搜尋。針對緩解期氣喘病人（P），針灸穴位刺激（I）、第一秒用力吐氣容積或尖峰呼氣流速、免疫球蛋白E、氣喘生活品質（O）及隨機控制試驗（D）。使用考科藍偏誤風險評估工具用於文章品質評估。結果：共納入38篇，3125人。介入措施包括敷貼、針刺、埋線（針）及注射等。總計使用42個穴位，使用頻率最高的穴位為肺俞、定喘、天突、膻中以及足三里。成效指標皆有統計意義。結論：本研究支持針灸穴位介入措施能改善緩解期氣喘病人的肺功能、免疫功能與生活品質。肺俞、定喘、天突為首要選擇，其次則需依介入方式而選用。

Background: Asthma care is focused on routinely controlling symptoms and lung function impairment in the long term. Although the evidences from systematic reviews support Chinese medicine in improving asthma effectively, acupuncture point used needs to be clarified for further clinical application. Purpose: This study aimed to determine the effect of acupuncture points on asthma at the remitting phase in terms of lung function, immune function, and quality of life. Methods: Seven electronic databases were used to search studies. Data was collected based on asthma patients in the remitting phase (P), acupuncture points interventions (I), forced expiratory volume in 1 second, peak expiratory flow, immune globulin E, asthma quality of life (O), and randomized controlled trial (D). The Cochrane risk of bias tool was used to assess methodologic quality. Results: A total of 38 articles was included, with 3,125 patients. The interventions involved herbal patching, acupuncture, catgut/needle embedding, and injection. A total of 42 acupuncture points were used, and the most frequently used ones in order were Feishu, Dingchuan, Tiantu, Danzhong, and Zusanli. Statistical significances were found in all outcomes. Conclusions: This study supports that acupuncture points interventions improve lung function, immune function, and quality of life for asthma patients in the remitting phase. Feishu, Dingchuan, and Tiantu are the first option of acupuncture points. Other acupuncture points can be targeted based on the type of interventions.