Background: Occupational skin diseases are important occupational diseases. The diseases are not often fatal nor often lead to disability, but the prevalence rates are high. However, the diseases are preventable and controllable most of the time. Objectives: To describe the epidemiology of occupational skin diseases in Taiwan based on the data from the Taiwan's occupational injury and disease notification system and discuss challenges that the system is facing. Methods: We obtained the data on occupational skin diseases from Taiwan's occupational injury and disease notification system between 2006 and 2013 and study the distributions of demographic characteristics and other variables of the cases. Results: The reported cases of occupational skin diseases in Taiwan have been increasing from 2006 to 2013. The use of the electronic reporting system has greatly improved the reporting rate. Occupations with the highest rates of occupational skin diseases are catering (22.1%), mechanical maintenance, milling machines, and metal processing (10.7%), and hairdressers and cosmetologists (8.6%). Conclusion: The data reported through the system are sufficient, and the sources of reporting are unevenly distributed. Consequently their use is limited in the identification of risk factors and high risk occupations, development of prevention and control strategies, etc. In order to obtain more useful reporting data, we suggest reviewing the information reported, modifying revise the reporting form, and increasing the incentives.