新上市流感病毒核酸快速檢測系統之效能評估

Evaluation of a New Rapid Nucleic Acid Test for Detection of Influenza Virus A&B

近日上市一套流感病毒核酸快速檢測系統──AlereTM i Influenza A&B，利用恆溫擴增反應技術原理，提供快速的流感病毒檢測。本次研究評估AlereTM i Influenza A&B檢測流感病毒的效能。總共測試60件臨床剩餘檢體，以Real-time PCR做為參考方法來評估AlereTM i的檢測效能。AlereTM i對於A型流感的檢測敏感性為100％，專一性為95.1％；對於B型流感的檢測敏感性為93.3％，專一性為100％。結果顯示AlereTM i具有相當好的檢測效能，且操作簡單，檢測時間僅需15分鐘，可提供臨床快速且準確的流感檢測結果。

Recently, a rapid detection system for influenza virus nucleic acid, AlereTM i Influenza A&B, was launched to provide rapid influenza virus detection using isothermal amplification reaction technique. This study evaluated the efficacy of AlereTM i Influenza A&B in detecting influenza virus. A total of 60 clinical samples were tested and Real-time PCR was used as a reference method to evaluate the detection efficiency of AlereTM i. AlereTM i has a sensitivity of 100% for detection of influenza A and a specificity of 95.1%; the sensitivity for detection of influenza B is 93.3% and the specificity is 100%. The results show that AlereTM i has a very good performance for detection influenza virus. AlereTM i operation is simple and the detention time is only 15 minutes, which can provide clinical rapid and accurate influenza test results.