The inhibitory effects of the green alga Chlorella pyrenoidosa against key enzymes relevant for type-2 diabetes were reported for the first time in the present work. The alga exerted its anti-diabetic actions by scavenging free radicals and/or chelating transition metals but not by suppressing reactive carbonyl species. The findings strongly supported the benefits of microalgae as functional foods in the prevention and alleviation of diabetes.
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