薑配製物之分析與安定性研究   全文下載

Analytical and Stability Studies of Ginger Preparations

薑是國人常用的藥物和食品。在歐美，薑的根部用於治療無食慾及暈車病。6-Gingerol是薑製劑品管的標誌物。本報告描述了6-gingerol的HPLC分析與安定性研究。其標準曲線之線性相關係數大於0.999。6-gingerol的HPLC分析方法已確認可作為安定性研究用，亦適合作為薑的預配方研究。本研究也報告薑配製物在不同酸鹼度下之安定性。

Ginger is one of the most frequently used ingredients in Chinese folk medicine and cooking. Ginger rhizome is used in treating/relieving appetite loss and motion sickness in western world. 6-Gingerol has been used as a marker substance of ginger. An HPLC analytical procedure of 6-gingerol was described. The correlation coefficients were greater than 0.999. The described HPLC procedure in this report has been validated and can be used to check 6-gingerol stability. It is also suitable for the preformulation study of ginger. The stabilities of ginger solution at different pHs were studied. The 6-gingerol contents in different preparations were evaluated. 薑是國人常用的藥物和食品。在歐美，薑的根部用於治療無食慾及暈車病。6-Gingerol是薑製劑品管的標誌物。本報告描述了6-gingerol的HPLC分析與安定性研究。其標準曲線之線性相關係數大於0.999。6-gingerol的HPLC分析方法已確認可作為安定性研究用，亦適合作為薑的預配方研究。本研究也報告薑配製物在不同酸鹼度下之安定性。