美髮染髮劑中氧化染髮成分分析方法探討及市售品之含量調查   全文下載

Determination of Oxidant Dyes in Hair Dyes by Gas Chromatography

以氣相層析法直接分析美髮染髮劑中aminophenol及phenylenediamine兩類氧化染髮成分之各三種異構物，和作為安定劑之catechol、pyrogallol及resorcinol等三種成分。並以自行配製之空白對照用美髮染髮液劑或霜劑，分別進行九種成分之0.25、0.5及1%三種濃度之添加回收試驗，除pyrogallol外其它八種成分添加濃度在0.5%及1.0%時，其回收率分別可達91.4～118.4%及85.5～103.2%。低溫貯藏可減緩氧化染髮成分消退。市售五十件檢體，其中檢出含aminophenol及phenylenediamine兩類氧化染髮成分者共33件（佔66%），標示不符者（包括標示該成分而未檢出及未標示而檢出者）共8件（佔16%），含量在原廠規格之90%至110%之外者共12件（佔24%），及無查驗登記字號但檢出氧化染髮成分者2件（佔4%）。該五十件檢體所添加氧化染髮成分之檢出範圍，均在行政院衛生署公告之限量範圍之內。 A capillary gas chromatographic method was adapted for the determination of nine dye components in oxidative hair dyes. An appropriate amount of sample was dissolved in 10 ml of alcohol containing 0.75% of diphenyl as internal standard. The solution was directly injected into an RTX-35 column, with temperatures ranging from 130-160°C. The recoveries achieved by this method, the effect of temperature and a survey of commercial hair dyes are discussed. The recoveries of nine oxidative hair dye components, i. e., three isomers of aminophenol, three isomers of phenylenediamine, catechol, resorcinol and pyrogallol, were in the range of 91.4-118.4% and 85.5-103.2% in liquid and cream samples, respectively. The temperature of storage affected the degradation of the oxidative hair dyes. Those stored at 5°C were degraded more slowly than those stored at 40°C. Fifty commercial hair dye smples were purchased between September 1993 and April 1994 from drugstores and supermarkets in Taipei. Sixty-six percent of these samples contained oxidative hair dye components. Sixteen percent of the smples were badly labeled. On the analyses of dyes, twenty-four percent of these samples were detected beyond the registration level ( 100 ± 10% ). Two samples without registration contained oxidative hair dyes Nevertheless, all of the samples were within the hygiene requirements ( aminophenol below 2%, phenylenediamine below 4% ) ."

A capillary gas chromatographic method was adapted for the determination of nine dye components in oxidative hair dyes. An appropriate amount of sample was dissolved in 10 ml of alcohol containing 0.75% of diphenyl as internal standard. The solution was directly injected into an RTX-35 column, with temperatures ranging from 130-160°C. The recoveries achieved by this method, the effect of temperature and a survey of commercial hair dyes are discussed. The recoveries of nine oxidative hair dye components, i. e., three isomers of aminophenol, three isomers of phenylenediamine, catechol, resorcinol and pyrogallol, were in the range of 91.4-118.4% and 85.5-103.2% in liquid and cream samples, respectively. The temperature of storage affected the degradation of the oxidative hair dyes. Those stored at 5°C were degraded more slowly than those stored at 40°C. Fifty commercial hair dye smples were purchased between September 1993 and April 1994 from drugstores and supermarkets in Taipei. Sixty-six percent of these samples contained oxidative hair dye components. Sixteen percent of the smples were badly labeled. On the analyses of dyes, twenty-four percent of these samples were detected beyond the registration level ( 100 ± 10% ). Two samples without registration contained oxidative hair dyes Nevertheless, all of the samples were within the hygiene requirements ( aminophenol below 2%, phenylenediamine below 4% ) .