Manufacturing industry has the highest occupational hazard rate in our country. Due to employees’ interaction with excessive machinery equipment in factories, there is a question of how to implement self-safety examinations and prevent machines from breaking down or artificial errors. Actually, most factories nowadays run the self-safety examinations artificially by using check verifying, inspection, and logging in. This approach consumes time and inefficiency. The objectives of this study are to guide PCB and metal finishing industry that establish inspection database system of the production equipment and health of the operation environment. The system can reach the goal of reducing occupational disaster through propagandize efforts of related associations of such industry. The inspection item in the checklist for each equipment include laws and regulation, relevant information from occupational hazard, literatures, and engineering experience etc. In addition, this work uses modern information techniques such as handheld intelligent devices to develop information system assisting district safety inspection. Furthermore, there are already 5 factories on trial to this system. The result show that this approach can improve the difficulties of the automatic inspection in industry and elevate managing efficiency.