血紅素H疾病病患脾臟切除後之漢斯氏體：病例報告

Heinz Bodies in Hemoglobin H Disease after Splenectomy: a Case Report

顯微鏡觀察周邊血液抹片紅血球，可用以鑑定和識別其形態異常。典型和特定紅血球形態助於準 確診斷各種疾病。然而，非典型的形態變化總是挑戰實驗室人員的能力。本病例報告為α地中海貧 血／血紅素H症患者，經脾切除術和膽囊切除術後，在紅血球上沒有典型的「咬痕細胞」特徵，如 漢斯氏體。這特殊的案例引起關注於具漢斯氏體變異紅血球之相關染色及形態。

Microscopic evaluation of RBC on a peripheral blood smear aids invaluably in identification and recognition of morphologic abnormalities. Typical and specific blood cell morphologies lead the observers to the accurate diagnosis of a variety of disorders. However, atypical morphological changes always challenge the laboratory personnel. Herein, we presented a case of alpha-thalassemia/ Hb H disease after receiving splenectomy and cholecystectomy, showing no typical “bite cells” characters in RBC which contained intact Heinz body inclusions. The specialty of this case might draw our attentions to variant Heinz body RBCs regarding the stain and morphology.