轉譯模式在長效鴉片類止痛藥的應用

Translational Medicine in Ultra-long Injectable Opioid Drug Discovery-- When abuse liability and toxicity meet analgesic efficacy

Opioid drugs are currently accepted as the most efficacious analgesic medicine throughout the world. With its dramatic pain-killing effect recognized ever since the prehistorical era, crude extract from poppy seeds has been widely used over in the European and Asian continents. However, the deleterious side effect profiles are known to develop after repeated and prolonged application.