化妝品皮膚過敏反應試驗與衛生化學檢查

THE TEST OF SKIN IRRITATION AND HYGINEIC CHEMISTS FOR COSMETICS

本試驗是以價購方式自台灣區北、中、南、東部等地區抽購市售之面霜化粧品類，並且參照 Draize 氏貼布試驗方法與判定標準，將家兔受刺激程度的輕重區分為無刺激性、輕微刺激性、中度刺激性及嚴重刺激性等四級。試驗結果刺激性陽性者則進行一般衛生化學檢查，分析其檢體中是否含汞塩，Bithionol 或 Hydroquinone Monobenzyl Ether 等。由試驗結果顯示154件檢體中判定為無刺激性者71件（46.1%），輕微刺激性者41件（26.6%），中度刺激性者42件（27.3%），然並未發現具有嚴重刺激性反應者。其中83件具有刺激性反應之檢體，經一般衛生化學檢查結果發現9件含有汞鹽（10.8%），但所有檢體均不含 Bithionol 及 Hydroquinone Monobenzyl Ether。

Samples for the study are face-dressing cosmetics which were bought from northern, middle, southern and eastern area of Taiwan. The method of Draize's Patch Test was followed. According to the criteria of judgement for irritation, the severity of symptoms of skin irritation is divided into four classes: no, mild, moderate and severe irritation. The samples showing positive reactions were further analyzed to check if their ingredients containing mercury, bithionol or hydroquinone mono benzyl ether. The results show that among the 154 samples, 71 are no irritation (46.1%), 41 mild irritation (26.6%), 42 moderate irritation (27.3%) and no case of severe irritation was found. The samples of 83 positive irritation were further analyzed. It wasfound that 9 samples contained mercury and no bithionol and hydroquinone mono benzyl ether were found.