生鮮雞肉及雞蛋中必利美達民(Pyrimethamine)之調查

SURVEY OF PYRIMETHAMINE RESIDUE IN RAW CHICKEN AND EGG

必利美達民（Pyrimethamine）此種藥物，以往被用於治療人之瘧疾，在動物方面，則常配合磺胺劑混合添加於飼料中作為抗菌之增強劑，以預防雞隻罹患原虫病。然過量之使用於雞隻中，則有可能殘留於雞蛋或雞肉中，經人攝食而進入人體。行政院衛生署於民國七十六年公告「動物用藥殘留量標準」中未多列必利美達民殘留量標準，故依規定不得檢出。本局曾於七十七年度調查過雞肉及雞蛋檢體各50件之必利美達民殘留量，結果均未檢出。對於目前養雞業者是否確實，遵守適當之停藥期而無藥物之濫用，實有必要加以瞭解。因此本調查就市面上抽購雞蛋及雞肉，以檢驗必利美達民殘留量。

CNS 11664 method was followed with the modification of dissolving the concentrate with 10% NaCl in 0.5N HCI in place of 0.5N HCl alone, the emulsification in fat removing with benzene could be eliminated. The test solution treated with DB-608 Capillary column and detected with GC/ECD yielded good results. The detection limit of pyrimethamine in raw chicken and egg was 0.1 ppm. From July 1995 to May 1996, 98 chickens and 22 eggs were collected and analyzed, but no evidence for pyrimethine was detected. The results showed evidence which indicated that either the chicken farmer obeyed the regulation or they might use of the other drugs.