慢性肝炎的病理機構肝纖維化的中西醫療

Pathophysiological Mechanism of Chronic Hepatitis - Liver Fibrosis Treatment in Trdaitional Chinese Medicine and Western Medicine

從肝纖維化病理，肝纖維化的有效治療主要包括針對原發病的病因治療，抗炎症治療及抑制肝內ECM生成、促進ECM降解等。不過，迄今為止，國外尚無實質意義治療肝纖維化的藥物。但中醫卻以病因以血瘀、痰凝著手，因此治療以活血利水為主。其基本方由「丹參、赤芍、穿山甲、山慈菇、澤蘭、水紅花子、生黃芪、茯苓、巴戟天」等組成。

According to the pathophysiology of liver fibrosis, the effective treatment of liver fibrosis should be aimed at pathogeny cure, anti-inflammatory medications, inhibiting ECM accumulation, and improving degradation of ECM. But so far, there is no known pharmaceutical drug for curing liver fibrosis in western medicine. In treating liver fibrosis, traditional Chinese medicine focuses on blood stasis and phlegm coagulation depending on causes. Activating blood flow and alleviating water retention are the primary methods The TCM herbal formula is composed of Danshen, Chishao, Chuanshanjia, Shancigu, Zelan, Shuihonghuatzu, Shenghuangqi, Fuling, and Bajitian.