洛神花之生物活性以及調節血脂作用之系統性文獻回顧

A Systematic Review of Bioactivities of Hibiscus sabdariffa and its Effectiveness in Managing Blood Lipid Profil

洛神花（Hibiscus sabdariffa）為一年生草本植物，傳統上認為洛神花具有清熱、涼血、解渴、消暑等作用，其花萼可被加工製成花茶、果醬及果凍，為台灣常見保健藥用植物之一。近幾年的文獻資料顯示，洛神花具有多樣生物活性，如：抗癌、降血壓、護肝等。血脂異常（dyslipidemia）為心血管疾病之主要危險因子，多年來在基礎動物試驗及人體臨床研究中，證實洛神花具有調節血脂的作用。洛神花具有顯著降低體內高血脂濃度，進而達到預防心血管疾病的發生。本文章系統性整理出洛神花的生物活性以及植物化學特性，並探討洛神花在調節血脂之作用機制。期望藉此文獻回顧深入瞭解與比較洛神花在調節血脂功效上的各式研究成果及此經濟作物在保健食品市場的應用概況。

Roselle (Hibiscus sabdariffa) is an annual herbaceous, easy-to-grow, widespread, and a plant long used as a medical herb in Taiwan. That is effective in treating heart-cleaning, blood-cooling, thirstquenching and refreshing in traditional medicine. The flowers of the plant are used in the form of tea, jellies and jams. Thus, it has traditionally been used as food or medicine without noticeable adverse effects. Many studies have been reported in chemical and biological functions of H. sabdariffa over the past few years. Similarly, it has been found to reduce blood lipids in animals and humans significantly. The present review is to summarize up-to-date information on the bioactivities and phytochemistry of H. sabdariffa, in regard to blood lipids from the literature. In addition to botanical studies and records of the traditional use of H. sabdariffa in dyslipidemia, scientific studies investigating improves blood lipid profile of this species and its active phytochemicals are presented and discussed. The present review provides preliminary information and gives guidance for further anti-dyslipidemia research and development of functional foods from H. sabdariffa.