僵直人症候群臨床精神症狀的多樣性

Complex Psychiatric Presentations in a Patient with Stiff-person Syndrome

目的：報告一位僵直人症候群個案，臨床上帶有許多精神症狀。個案報告：一位60 歲 女性病人在被診斷為僵直人症候群前十年，經歷了憂鬱、焦慮等症狀起伏，在僵直人症候群 確診後兩年，出現失憶及情緒症狀。結論：僵直人症候群為一罕見神經學疾患，經常合併出 現複雜的精神症狀，但仍需更多研究了解其與精神症狀間的關係。

Objective: We report a case of stiff-person syndrome in a female patient, who presented multiple psychiatric symptoms and signs. Case Report: A 60-year-old Asian female patient had a 10-year-history of experiencing waxing and waning depression and anxiety symptoms before being diagnosed with stiff-person syndrome. Amnesic symptoms were occurred together with mood symptoms and stiffperson syndrome two years after having the neurological diagnosis. Conclusion: Stiff-person syndrome, an uncommon neurological disorder, is frequently comorbid with psychiatric symptoms and signs. This syndrome is complex and needs further investigations.