顱痛散對偏頭痛相關參數的影響

THE EFFECT OF RU TONG SHAN ON CORRELATION PARAMETER OF MIGRAIN

72 例偏頭痛患者隨機分成兩組，對照組 35 例服用天麻密環片，治療組 37 例服用顱痛散（由川芎、牛膝、芍藥、細辛、僵蠶等組成），療程 3 個月後，治療組在上述前三個指標偏頭痛發作持續時間、每月發作頻度、頭痛指數及 TCD（ transcranial doppler）所示大腦中動脈（ MCA）、大腦前動脈（ ACA）、大腦後動脈（ PCA）的血流速度（ Vm）在治療 1、 2、 3 個月後與治療前有明顯差別（P < 0.01 or P < 0.05），且前兩者治療後與對照組治療後存在顯著差異（P < 0.01or P < 0.05）。可見顱痛散對血流加快、血管痙攣的偏頭痛患者能明顯改善其血流速度與痙攣狀態，從而影響偏頭痛發作時間、頻度、指數及 TCD 某些參數，但對血流速度慢並血管擴張的偏頭痛患者無明顯影響。TO study the effect of Ru Tong Shan to migrain patients on continual time of headache, frequency of every month, headache index and transcranial doppler (TCD) index variations. To divide 72 migrain patients into two groups randomly of contrast group and treatment group. And 35 patients of contrast group took Gastrodia elata BL. Tablets, while 37patients of other group took Ru Tong Shan. The period was three months. The first three indexes and Vm of middle cerebra artery (MCA), anterior cerebra artery (ACA), and posterior cerebra artery (PCA) in TCD of treatment group are obviously changed, because of took the drug (P < 0.01 or P < 0.05). And the first two indexes between treatment group and contrast group have obvious difference (P < 0.01 or P < 0.05). Ru Tong Shan have obvious effect to migrain patients who have quick blood speed and spasm of blood vessels. It can better the patients’ blood speed and spasm condition, then affect, the patients continual time, frequency, index and some TCD the patient who have slow blood speed and dilated blood vessels.