Exchange between different bodies of medical knowedge has been the source of mutual stimulation that has provided a major driving force of the development of medicine and hygiene. This paper looks at the history of exchanges between China and other countries, laying emphasis on the massive importantion of foreign medicine into China against the background of imperial invasion. The introduction of Western medicine into China brought Chinese medicine into conflict with it. Chinese medicine tried to secure its survival and development against the onslaught of modern medicine by allowing a confluence of the two traditions, whereby Chinese medicine could adopt Western medical theories to supplement its own and stimulate its development. Although different proponents had different theories and ideas about what form the confluence would take, they all agreed in the hope Chinese medicine could be improved by some sort of confluence. As a result, this gradually became the mainstream approach in Chinese medicine, but it attained little success. In the 1950s, emphasis was placed on developing Chinese medicine and on the notion that a firm mastery of modern scientific research was the key developing Chinese medicine. With this, a move toward the integration between Chinese and Western medicine came into being. The scientific research that followed as part of this move gradually led to the accumulation of experience, methods, and approaches. This paper summarizes the stage-by-stage development or integrated medicine and the methods and approaches that it has applied.