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篇名
中藥「清鼻散」治療小兒過敏性鼻炎之研究
並列篇名
The Therapeutic Effect of Chinese Medical Preparation "Qing Bi San" on Allergic Rhinitis
作者 蔡順輝
中文摘要
目前對於過敏性鼻炎的病因為主里及治療的方法雖然已有很大的進展,但因西醫藥療法仍有祟些不能克服的副作用,中醫藥的使用期能彌補其不足。從1993 年10 月到1994 年5月,中國醫藥學院附設醫院中醫兒科門診收集48 位鼻過敏患者,其中男性26 位,女性22位,年齡6 歲到11 歲,平均8.1 歲。依中醫辨證的方法分為熱盛型28 位與寒盛型20 位二組,給予中藥「清鼻散」(辛夷清肺飲合知柏地黃丸)連續治療12 週後觀察臨床症狀與實驗室槍查值的變化。結呆顯示熱盛型忠者的主觀症狀如鼻塞、流鼻水、打噴壇、鼻癢都有改善。鼻黏膜腫脹度、周邊嗜伊紅球及鼻液嗜伊紅球皆至有意義的下降(p < 0. 05),但血清IgE 及經QUIDEL Reflectance Analyzer 測得之Mite DF 及Mite DPT 平均值並無統計學上的差別。寒盛型患者經治療後其症狀及各項實驗室槍查值皆無變化。治療期間除了6 位患者出現暫時性冒脫脹痛,此外並無其他的副作用。本研究的結果說明了應用中醫辨證的方法以中華治療熱盛型過敏性鼻炎可取得良好的效果。
英文摘要
Though the Western medical understanding of the pathogenesis and treatment of allergic rhinitis has improved greatly through recent years, Western medication causes certain side-effects. It is our hope to find a solution from traditional Chinese medicine. The study covers 48 children diagnosed as suffering from allergic rhinitis by the Department of Traditional Pediatrics of the China Medical College Hospital from Oct. 1993 to May 1994. There were 26 males and 22 females. Their ages ranged from 6 to 11 with an average of 8.1. According to Chinese medical pattern identification, 28 of them displayed heat-predominant patterns and 20 of them displayed cold-predominant patterns. They were treated with a Chinese medical preparation ”qing bi san”, (comprising ”xin-yi qing fei yin” plus ”zhi bo di-huang wan”) for 12 weeks. After the treatment, the heat-predominant pattern patients improved in subjective symptoms including nasal obstruction, rhinorrhea, sneezing and itching. The degree of hypertrophy of nasal turbinates showed statistically significant decrease. In laboratory data, they showed significant decrease (p<0.05) in total eosinophil count and nasal eosinophilia. They showed, however, no significant difference in serum IgE value and Mite DPT, and Mite DF indexes gained through QUIDEL Reflectance Analyzer. On the other hand, the cold-predominant pattern patients revealed no improvement in signs & symptoms nor in laboratory data after the treatment. There were no side effects except temporary stomach fullness and pain in 6 cases, which can be attributed to the medication. Clearly, this study concludes that the application of traditional Chinese pattern identification in diagnosis, combined with Chinese formula in treatment of allergic rhinitis is effective, as far as the heat-predominated pattern patients is concerned.
起訖頁 27-36
關鍵詞 過敏性鼻炎中藥清鼻散Allergic rhinitisTraditional Chinese medicineQing Bi San
刊名 中醫藥雜誌  
期數 199503 (6:1期)
出版單位 衛生福利部國家中醫藥研究所(原:國立中國醫藥研究所)
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