期刊連結：http://www.gouthyperuricemia.org

Purpose: The interest in hypouricemia has begun to increase with a better understanding of uric acid transporters. However, it is always overlooked and has not received enough attention. We aim to review related literature to provide a deeper understanding of hypouricemia.

Findings: Hypouricemia has a high prevalence. It is always accompanied by uric acid synthesis insufficiency or redundant renal excretion of uric acid. Hereditary renal hypouricemia stems from gene mutation. It is easy to undergo exercise-induced acute renal failure and/or nephrolithiasis. The treatment for hypouricemia is inconclusive.

Conclusion: Hypouricemia is increasing in prevalence. It is related to underlying diseases and medications. Hypouricemia may be extremely harmful to the body and warrants more attention from clinicans.