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Objective: To determine the serum uric acid level, the prevalence of hyperuricemia and its distribution within residents in the Chongqing area. Furthermore, we analyzed the relevance of hyperuricemia with metabolic syndrome (MS), urine pH value and red blood cell distribution width.

Methods: Statistics were taken for participants who underwent a health screening during the period from January 2014 to December 2014 at the Southwest Hospital Health Management Center. Hyperuricemia was defined as serum uric acid level >420 μmol/L for males and serum uric acid level >360 μmol/L for females. The metabolic syndrome was defined according to the criteria recommend by China Adult Dyslipidemia Prevention Guide (2007).

Results: This study included 110,777 participants (65,667 men, mean age: 45.69 ± 12.44 years and 45,110 women, mean age: 45.33 ± 12.38 years). The prevalence of hyperuricemia is generally 21.38%. Moreover, it’s 30.33% in men and 8.35% in women. The prevalence is significantly higher in men than women. The average serum uric acid level is (385.41 ± 82.65) μmol/L for male and (275.63 ± 60.45) μmol/L for female. Meanwhile, hyperuricemia accompanied with metabolic syndrome is more prevalence in men (36.73%) than in women (26.99%).

Conclusion: The prevalence of hyperuricemia in Chongqing at of the higher end in the country. Hyperuricemia is more likely to be associated with metabolic syndrome. In addition, uric acid level was proportionately associated with hyperglycemia in women, but the relationship between hyperuricemia and fasting glucose did not show the same trend in men.