| 英文摘要 |
Relatives and spouses of chronic hemodialysis patients have been found to have a high risk of chronic kidney disease (CKD). The identification of localized risk factors in this population is an important part of the CKD prevention policy in Taiwan. Our study aimed to investigate prevalence and risk factors of CKD in the relatives and spouses in hemodialysis patients. A total of 257 family members were recruited, including 161 first- and second- degree relatives and 96 spouses. Information was collected through urine samples, biochemical blood tests and lifestyle (smoking, alcohol consumption, betel nut use, sleeping habits and exercise frequency) for analysis. Patient families’ demographics, disease history, family history, medication history and lifestyle were set as the variables for the analysis of prevalence and related factors with potential CKD patients. Our results found that (1) potential prevalence rate of CKD in relatives and spouses was 14%. (2) Chi-Square analysis revealed that relationship to the patient, age, education, history of gout, long-term use of uric acid lowering agents and health supplements (OR: 2.28) had a significant influence on CKD incidence. (3) Logistic regression analysis found the predictive variables for CKD prevalence were gender, smoking, alcohol consumption and family history of cardiovascular disease. Our study demonstrated that the factors associated with the prevalence of CKD were being the patient’s spouse, older age, low level of education, history gout and use of gout medication, family history of cardiovascular disease in the family, smoking and alcohol consumption. The family members of dialysis patients should therefore pay more attention to their understanding of the disease and proper lifestyle in order to reduce the prevalence of CKD. |
