| 英文摘要 |
Results: A total of 79,052 men and 72,587 women were enrolled. The prevalence of gallstone disease read respectively 5.9% overall, 6.4% in male subjects, and 5.3% in female subjects. Overweight and obesity increased the risk of gallstone disease by nearly 50%. In multivariate analysis controlled by age, body mass index, history of hypertension and diabetes, lower HDL-C emerged to be positively associated with gallstone disease in both genders, adjusted OR1.14 (1.08-1.21) in men and adjusted OR 1.28 (1.17-1.48) in women. Moreover, hypercholesterolemia (OR 1.13 [1.02-1.25]) and high LDL-C (OR 1.1 [1.06-1.27]) were further identified as the risk factors for gallstone disease in women. |
