李東垣所著《內外傷辨惑論》，詳述了內傷與外感的辨別與內傷病之治療。書中46個主要處方，體現了東垣遣方用藥之思想。
本文以王好古《湯液本草》為藍本，統計分析《內外傷辨惑論》主方之「用藥頻次」、「藥類法象」、「升降」、「方劑歸經」、「主治病機」，以分析《內外傷辨惑論》中東垣之學術思想，其結果如下：《內外傷辨惑論》全書主要方劑的藥物出現頻次共為398次，並以「濕化成」類之甘草、陳皮、白朮、人參四者居首。全書主方用藥頻次之藥類法象統計，以「濕化成」類之147次居首。全書主方以升浮為主。主方歸經，前三名分別為入胃經佔48.9%、入脾經佔22.5%、入肺經佔12%。主方之主治病機，以治療邪戀為主。故《內外傷辨惑論》一書用藥以「濕化成」之脾胃藥為重。方劑性質偏升浮。方劑歸經及功能，以入胃經祛食積最多，其次為入脾經補氣，兩者即佔方劑歸經之7成，故《內外傷辨惑論》明顯與治療脾胃最相關。另有部分方劑入肺，與溫病之治療有關。

The book “Nei Wai Shang Bian Huo Luen” written by Dong-Yuan Li records the differences of diseases caused by internal and external factors as well as the treatment of diseases caused by internal factors. The 46 main prescriptions contained inside the book demonstrate Dong-Yuan Li’s style and reasoning when composing an herbal prescription. This article reviewed the main prescriptions of “Nei Wai Shang Bian Huo Luen” with “Tan Ye Ben Cao” written by Hao-Gu Wang, and statistically analyzed the formulas according to: frequency of use of the various herbs, grouping of herbs, up-lifting and down-bearing nature, channel entry and therapeutic mechanism. As a result, herbs are used in the main prescriptions for 398 times. The most frequently used herbs are Gan Cao (Glycyrrhiza glabra), Chen Pi (Citrus reticulata), Huang Qi (Atractylodes macrocephala) and Ren Shen (Panax ginseng). These herbs all belong to the “Dampness transforming” group which was also the most frequently showing pharmacological group of herbs with 147 occurrences. Most main prescriptions of the book are up-lifting in nature. The three most common channels used were the stomach channel (48.9%), spleen channel (22.5%) and lung channel (12%). The main therapeutic mechanism used is “Removal of lodged pathogenic influences”.  So the most frequently showing pharmacological group of herbs is the “Dampness transforming” group. Most main prescriptions of the book are up-lifting in nature. “Nei Wai Shang Bian Huo Luen” was found to be mostly associated with the stomach (removal of food accumulation) and spleen (supplementing Qi) with the two channels associated to 70% of all prescriptions. Furthermore, the lung channel prescriptions were related to febrile diseases.