篇名 | 由含羞草根部得到兩個新的二萜類抗菌成分 |
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並列篇名 | Two New Antimicrobial Diterpenoids from the Roots of Mimosa pudica |
作者 | 疏偉傑、何姣青 |
中文摘要 | 從含羞草根部分離得到兩個新的二萜化合物,命名為19-O-trans-feruloyl-labd-8(17)-en-15,19-diol (1) and 19-O-[(E)-3’,4’-dimethoxy cinnamoyl]-labd-8(17)-en-15,19-diol (2)。化合物1-2對酵母菌和細菌具有抗菌活性,對厚皮馬拉色菌的抗菌活性最強,其次為白色念珠菌和金黃色葡萄球菌,抑菌圈在12-16 毫米的範圍內。 |
英文摘要 | From the root of Mimosa pudica L. (Fabaceae), two new diterpenoids, named 19-O-transferuloyl- labd-8(17)-en-15,19-diol (1) and 19-O-[(E)-3’,4’-dimethoxy cinnamoyl]-labd-8(17)-en- 15,19-diol (2) had been isolated. Their structures were determined by analysis of spectroscopic data, including 1D and 2D NMR. Compounds 1-2 showed antimicrobial activity against two yeast and two bacteria tested. The strongest activity was observed against Malassezia pachydermatis, followed by Candida albicans and Staphylococcus aureus in the range of 12-16 mm. |
起訖頁 | 223-229 |
關鍵詞 | Mimosa pudica、 diterpenoids、 antimicrobial activity |
刊名 | 中醫藥雜誌 |
出版單位 | 衛生福利部國家中醫藥研究所(原:國立中國醫藥研究所) |
期數 | 201312 (24:2期) |
DOI | 10.3966/101764462013122402003 複製DOI DOI申請 |
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