This study investigates the seismic reinforcement of older reinforced concrete buildings in Taiwan. Many of these buildings were designed with non-ductile structures and non-ductile reinforcements to resist seismic forces, so they are prone to compressive failure or even collapse during earthquakes. Traditional seismic reinforcement methods can often interfere with the everyday functions of the building, making them unsuitable for residential purposes. The study uses domestically produced larch Cryptomeria japonica made cross-laminated timber (CLT) as a retrofit material to address this issue, effectively improving non-ductile structures’ seismic resistance. The experiment includes four non-ductile reinforced concrete frames, with one control group and the other three groups retrofitted by CLT, Cross-laminated timber-bamboo (CLTB), and RC as shear walls. The experimental results show that the maximum horizontal shear force of the non-ductile frame is 450 kN, with a maximum inter-story drift angle of 3%, indicating typical flexural-shear failure. The maximum horizontal shear force of the RC-reinforced frame is 1,350 kN, with a maximum inter-story drift angle of 1%, which increases the horizontal shear strength by three times but leaves 50% of the deformation capacity. The maximum horizontal shear force of the CLTB frame is 1,100 kN, 2.35 times that of the non-ductile RC frame, with a maximum inter-story drift angle of 2.5%, satisfying the 2% deformation requirement for a building with walls. The maximum horizontal shear force of the CLT-reinforced frame is 1,000 kN, with a high inter-story drift angle of 4%, showing good bilinear behavior in lateral force-displacement curves.