Objective: This study aimed to analyze the process and outcomes of withdraw-ing life-sustaining treatment (LST) in a regional hospital. Methods and Methods: This retrospective study collected data from patients who met the criteria for pallia-tive shared care and underwent withdrawal of LST at a regional hospital in northern Taiwan between March 2016 and December 2023. The processes and outcomes were analyzed. Results: A total of 208 patients withdrew LST, including 95 males and 113 females, with a mean age of 83.2 ± 12.1 years. The most common underlying disease was renal failure (68 patients). In 187 cases, family members signed the consent form for withholding cardiopulmonary resuscitation and LST. The most frequently withdrawn intervention was endotracheal intubation (54 patients). The average time from LST withdrawal to death was 4.95 ± 7.8 days. The majority of patients (171, 82.2%) died after LST withdrawal, while 37 patients survived, with 13 (6.3%) dis-charged for home palliative care. The average time from LST withdrawal to death for those discharged was 6.7 ± 8.6 days. The hospital or this study does not have dedicated oncology or palliative care units, most LST withdrawals occurred in gen-eral wards, predominantly for non-cancer diagnoses (83.2%). While general nursing care was provided, the delivery of patient-centered spiritual and end-of-life care ser-vices in non-palliative settings with limited resources remains a challenge. The findings can inform in-service education and care for terminally ill patients in non-palliative wards.