In this paper, we use two screen-printed electrodes to design a chloride ions concentration sensor for the water quality detection. The chloride ions concentration sensor, which is designed by a Field Programmable Gate Array (FPGA), a charge transfer circuit and a 12-bit analog to digital converter (ADC), can be used to evaluate the quality of pure water, to evaluate the concentration of dissolved minerals in wastewater, to estimate the number of samples used for chemical analysis of water, and to check the correctness of chemical analysis results.