Individuals with disabilities often face complex gender-related problems because of their special needs. In particular, women with disabilities often face many challenges pertaining to reproductive health, gender-based violence, and chronic disease management. In addition, transportation difficulties and financial constraints further hinder their access to continuous chronic disease care and management. Compared with women, men with disabilities have higher needs for mental health and accident prevention; however, social expectations and gender role pressure often deter such men from seeking psychological support. Transgender individuals with disabilities have complex requirements related to gender-affirming treatment and often face discrimination and misunderstanding in medical settings. To solve this problem, medical institutions should enhance gender awareness among their medical personnel to promote inclusivity and improve service quality. Therefore, it is necessary to strengthen the focus on the specific gender health needs of individuals with disabilities from various aspects. This includes providing gender-sensitive training courses, and establishing effective support mechanisms, such as measures to prevent gender-based violence prevention and offering psychological support services. These efforts are essential to ensure that individuals with disabilities receive equal rights and safety in addressing their unique gender issues.