早期營養介入對癌症病人營養狀態與生活品質的影響

The Effect of Early Nutritional Intervention on the Nutritional Status and Quality of Life among Cancer Patients

目的：本研究旨在透過個別化早期營養介入，改善營養不良風險癌症病人的營養狀態，並降低治療併發症，特別是頭頸癌、食道癌、胃癌、胰臟癌病人。

方法：研究納入2022年3月至2023年5月期間在台北慈濟醫院診斷為頭頸癌、食道癌、胃癌、胰臟癌病人。治療前後收集體位測量數據（體重）、白蛋白值、營養評估和生活品質問卷調查。

結果：研究發現，透過個別化營養介入後，所有癌症病人共40人，在治療後平均體重變化下降為1.6公斤，體重維持或增加為25人(62.5%)，其中體重減輕為15人(37.5%)，而白蛋白值治療前為3.74±0.55 mg/dL，治療後為3.9±0.36 mg/dL (p=0.0327)，整體營養狀況有顯著提升，在治療後生活品質下降的程度也有所改善。

結論：本研究證實，早期診斷和介入癌症病人營養不良或有營養不良風險的人，透過個別化的營養介入，可以改善癌症病人的營養狀態和維持生活品質。

 

Purpose: The study aimed to investigate the effect of individualized nutritional intervention on the nutritional status of cancer patients, specifically those with head and neck cancer, esophageal cancer, gastric cancer, and pancreatic cancer.

Methods: Patients diagnosed with head and neck cancer, esophageal cancer, gastric cancer, or pancreatic cancer at Taipei Tzu Chi Hospital during March 2022 to May 2023 were enrolled in this study. The collection of anthropometry data (body weight) and albumin values, nutrition assessments, and questionnaire survey on quality of life were conducted before and after treatment.

Results: With individualized nutritional intervention, the mean change of body weight in all of the 40 enrolled cancer patients after treatment was -1.6 kg. 25 (62.5%) of them were able to maintain or gain weight, while 15 (37.5%) of them lost weight. The nutritional status of the enrolled cancer patients reported significant improvement [all cases, albumin (mean± standard deviation, SD): baseline=3.74±0.55 mg/dL; after=3.9±0.36 mg/dL; p=0.0327]. Mitigation was also observed in the post-treatment decrease in quality of life.

Conclusion: These findings suggest the necessity of early identification of malnutrition or risk of malnutrition in cancer patients to facilitate individualized nutritional intervention for improving the nutritional status and overall well-being of the patients.