In recent years, numerous fires in healthcare institutions in Taiwan have resulted in casualties, highlighting the importance of environmental safety in medical facilities. With growing public concern over the safety of healthcare environments, hospitals must prioritize fire safety, focusing on both patient and fire safety measures. Chiayi Hospital staff participated in the 2023 Fire Safety Module counseling project of the Safe Healthcare Environment Advisory Program to establish a safe medical environment. This program incorporated guidance from external patient safety and fire safety experts to construct safe treatment environments. A thorough inventory of equipment and emergency response plans was conducted, involving the collaborative participation of all staff members to identify institutional vulnerabilities and enhance emergency response capabilities in the event of a fire. On-site inspections and guidance leveraged the counsel of domestic and international experts and scholars to address risk factors unique to the hospital, discussing solutions and areas of improvement to prioritize in accordance with the hospital’s limited resources at hand. This paper outlines Chiayi Hospital’s experiences in the Safe Healthcare Environment Advisory Program to benefit other hospitals and enhance hospital environmental safety throughout Taiwan.