Telemedicine has been developed in different processes in each country. International academic circles have discussed the causes of difficulty in developing or spreading the use of telemedicine, which is affected by factors such as technological infrastructure, social progress, medical environment, policies, differences in insurance systems, public needs, medical habits, and cultural backgrounds. In 2021, the Institute for Healthcare Improvement from the United States of America published a white book on telemedicine development. The white book advocates for providing a high-quality virtual care model and developing a safe, equitable, and person-centered telemedicine framework. The framework consists of 6 elements: access, privacy, diagnostic accuracy, communication, psychological and emotional safety, and human factors and system design. The white book also provides practical suggestions on telemedicine. Telemedicine has become a new medical normal for various countries in the post-COVID era. In developing telemedicine, healthcare systems and providers must not only maintain the quality of care, but also pay attention to the unique and potential accidents and risks involved in virtual care. The results of this study provide a key reference to health care systems and personnel in establishing a safe, equitable, and person-centered telemedicine system.