Fever is a common clinical symptom and it is crucial to assess the etiology for appropriate treatment.This article describes the nursing experience of a 67-Year-Old male patient with recurrent fever, ac-companied by chills, abdominal pain, and general soreness. Septic shock and multiple organ failure further developed. A thorough history was performed by the author as a nurse practitioner. Physical assessments, and primary care were conducted between 12th November and 10th December 2019. Ac-cording to the history, the patient was bitten by a monkey prior to the episode. Scrub typhus and/or leptospirosis co-infection were highly suspected. Immediately after the blood tests for scrub typhus and leptospirosis, empirical antibiotic treatment was applied. Scrub typhus was confirmed on 27th November, 2019. Septic shock, respiratory failure, gastrointestinal tract symptoms, hepatitis and renal failure gradually resolved after the treatments. The patient fully recovered and was discharged without sequelae. Thorough history taking including travel, occupation, contact, and cluster (TOCC) is very important to identify febrile diseases. For timely treatment, including scrub typhus into differential diagnosis for the patients with high risk is suggested, despite no eschar was found.