In this paper, a wireless continuous acid-base detection system for aquaculture is proposed to detect the pH value of aquaculture’s water in the center position, by means of infrared remote-control vessel and Bluetooth wireless transmission. In the proposed system, we adopt the Silicon Labs EFM32 microprocessor to act as system control unit. This microprocessor will detect the voltage generated by the UltraE pH strip and transmit it to the Bluetooth module. Then, the Bluetooth module will transmit the measured pH value to the computer on the shore. Taking advantage of the LabView user interface for making a real-time pH plot, the computer will show the pH results. Moreover, we design an infrared remote-control vessel to place the proposed system for the pH value of aquaculture’s water in the center position detection, while the vessel is moving. In system verification, we adopt the commercial acid-base detector, the UltraE pH strip, and the proposed system to detect the pH value of different concentration solution for verification. Experimental results show that the proposed system has the same trend as the commercial acid-base detector. In conclusion, the proposed system can directly detect the pH value of aquaculture’s water in the expected position, by moving an infrared remote-control vessel to the desired place, without the need of actual sampling.