Nurse practitioners (NP) are the only advanced nurse practitioners with a national license in Taiwan.NPs work with physicians to provide medical treatment and perform nursing care services. NPs must pass written and oral exams to obtain practicing license. The required clinical reasoning ability is difficult to evaluate by using written tests. Therefore, the objective structured clinical examination (OSCE) is chosen to examine practical and clinical ability of future NPs. OSCE scripts are called “living exam questions” and require standardized patients (SP) to play the role in the determined context. Lack of consistency in SPs’ live-action affects the performance of candidates. In the past, candidates’ appeal due to SP performance was about 2 to 3 times per year. Standardized Patient Trainer (SPT) plays a vital role in SP training. In the past, senior NPs or senior emergency medical technicians (EMT), served as the SPT in oral script training, depending on the organizer. There is no pre-SPT training course in the designed process. The quality of SPs’ performance is important because it affects the candidates’performance in the oral exam. Thus, the purpose of this study is to investigate the improvements of SPT’s learning satisfaction and candidates’ appeal rate after SPTs training program adopting the script training module course. A total of 21 SPTs participated in the training program, including 6 senior NPs and 15 senior EMTs. The study adopted the “Learning satisfaction questionnaire of standardized patient trainer training course, (LSQSPTTC), “including three domains of “curriculum materials,”“lesson training,” and “script practice training.” Also, use the Likert 5-point scale (1-very dissatisfied and 5-very satisfied) to evaluate the learning effectiveness. Furthermore, the number of incidents of candidates’ appeal due to SP performance was provided by the examination organizer. The learning satisfaction after the oral exams is higher than the completion of the script training. The domain of “script practice training” had a statistically significant difference (p < 0.05), indicating that SPTs satisfied with the training module courses. Furthermore, there is no appeal incident due to SP performance in the 109th Republic of China for the first time. The results support that the training module courses can effectively prepare SPTs to be competent for SP scripts training dedicated to NP screening exams.