抗藥性細菌的崛起：抗藥性機制與抗生素敏感性試驗

Antibiotic Resistance in Bacteria: Mechanisms and Antibiotic Susceptibility Testing Methodologies

抗藥性細菌的出現是全世界公共衛生的一大難題。細菌抗藥性造成臨床上抗生素治療受到限制，並提高了醫療照護與社會的成本。本篇綜論介紹抗生素的起源，細菌抗藥性與機制，以及目前臨床微生物實驗室對於細菌抗藥性的檢驗技術。

The emergence of antibiotic-resistant bacteria is a public health conundrum worldwide. The resulting antibiotic resistance in bacteria causes limited treatment options for clinicians and has a significant impact on patient care and the financial costs to society. This mini-review contains a section on the history of antibiotics, antibiotic resistance in bacteria and the underlying mechanisms of this resistance and the current diagnostics for bacterial drug resistance in use in the clinical microbiology laboratory.